Preoperative transcatheter arterial chemo-embolization for locally advanced breast cancer —Application of new thrombotic materials—

The anticancer drugs, Adriamycin and Mitomycin were individually immobilized on absorbable gelatin materials, together with a blood clotting factor, Factor XIII and thrombin, using a special technique. The materials were applied as thrombotic agents in preoperative therapeutic transcatheter arterial embolization for patients with locally advanced breast cancer. This approach to preoperative management proved to be superior to intra-arterial infusion therapy currently applied in various clinics. Key wordsblood clotting factor XIII-transcatheter arterial chemoembolization (TACE)-(locally advanced) breast cancer