Complete Response of Esophageal Cancer Achieved by Combination Therapy with 5-Fluorouracil, Low-Dose Cisplatin, and Radiation: Report of a Case

per day, from days 1–5 combined with the daily administration of low-dose cisplatin, 10 mg/m2 per day before each fraction of radiation, given as 2 Gy each time, throughout the entire treatment period of 3 weeks beginning on day 1. The benefits of our preoperative chemoradiation therapy included no severe side effects, down-staging and resectability of the tumor, as well as a pathological complete response, which could prolong the survival time. Our experience of this case prompts us to recommend the concurrent daily preoperative chemoradiation therapy for patients with locally advanced esophageal cancer. Key Words: esophageal cancer-chemoradiation-cisplatin-5-fluorouracil-radiosensitization(Received for publication on June 20, 1997; accepted on Jan. 6, 1998)